ncRNA name | hsa-miR-421 |
ncRNA Category | miRNA |
Disease name | cataract |
Species | Homo sapiens |
Tissues/Cell_line | anterior lens capsules; human lens epithelial cell line SRA01/04 |
Methods | transfection, luciferase reporter assay, flow cytometry, qRT-PCR, Western blot, immunoprecipitation |
Expression pattern | down-regulated |
Functional description | TUG1 modulated lens epithelial cell apoptosis through miR-421/caspase-3 axis. |
PubMed ID | 28392351 |
Year | 2017 |
Title | TUG1 promotes lens epithelial cell apoptosis by regulating miR-421/caspase-3 axis in age-related cataract. |
Drug-related ncRNA | NO |
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