logo

        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of cataract
ncRNA name hsa-miR-421
ncRNA Category miRNA
Disease name cataract
Species Homo sapiens
Tissues/Cell_line anterior lens capsules; human lens epithelial cell line SRA01/04
Methods transfection, luciferase reporter assay, flow cytometry, qRT-PCR, Western blot, immunoprecipitation
Expression pattern down-regulated
Functional description TUG1 modulated lens epithelial cell apoptosis through miR-421/caspase-3 axis.
PubMed ID 28392351
Year 2017
Title TUG1 promotes lens epithelial cell apoptosis by regulating miR-421/caspase-3 axis in age-related cataract.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.